Colchinoic acid
| Code | Size | Price |
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| TAR-T31001-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Colchinoic acid is a biochemical that has been shown to bind to tubulin.
CAS:
6714-14-3
Formula:
C21H23NO6
Molecular Weight:
385.416
Purity:
0.98
SMILES:
COc1cc2CC[C@H](NC(C)=O)c3cc(ccc3-c2c(OC)c1OC)C(O)=O
References
1. Djurdjevic S, Yang F, Green JR. Intramolecular Nicholas reactions in the synthesis of dibenzocycloheptanes. Synthesis of allocolchicine NSC 51046 and analogues and the formal synthesis of (-)-allocolchicine. J Org Chem. 2010 Dec 3;75(23):8241-51. doi: 10.1021/jo101953n. Epub 2010 Nov 8. PubMed PMID: 21058661.
2. Hastie SB. Spectroscopic and kinetic features of allocolchicine binding to tubulin. Biochemistry. 1989 Sep 19;28(19):7753-60. PubMed PMID: 2611212.
3. Deinum J, Lincoln P. Binding to tubulin of an allocolchicine spin probe: interaction with the essential SH groups and other active sites. Biochim Biophys Acta. 1986 Mar 28;870(2):226-33. PubMed PMID: 3006777.