Cysteinesulfenic acid

TargetMol
Product Code: TAR-T31159
Supplier: TargetMol
CodeSizePrice
TAR-T31159-5mg5mg£850.00
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Quantity:
TAR-T31159-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T31159-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Cysteinesulfenic acid is a protein-sulfenic acid involved in enzyme catalysis, redox regulation, and signal transduction.
CAS:
73243-12-6
Formula:
C7H14N2O3S
Molecular Weight:
206.26
Purity:
0.98
SMILES:
CCCNC(=O)SC[C@H](N)C(O)=O

References

1. Gupta V, Yang J, Liebler DC, Carroll KS. Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles. J Am Chem Soc. 2017 Apr 19;139(15):5588-5595. doi: 10.1021/jacs.7b01791. Epub 2017 Apr 10. PubMed PMID: 28355876; PubMed Central PMCID: PMC5898444. 2. Gupta V, Carroll KS. Rational design of reversible and irreversible cysteine sulfenic acid-targeted linear C-nucleophiles. Chem Commun (Camb). 2016 Feb 25;52(16):3414-7. doi: 10.1039/c6cc00228e. PubMed PMID: 26878905; PubMed Central PMCID: PMC4830130. 3. Pan J, Carroll KS. Light-Mediated Sulfenic Acid Generation from Photocaged Cysteine Sulfoxide. Org Lett. 2015 Dec 18;17(24):6014-7. doi: 10.1021/acs.orglett.5b02981. Epub 2015 Dec 7. PubMed PMID: 26641493; PubMed Central PMCID: PMC4699549. 4. Yamanaka Y, Kato Y, Hashimoto K, Iida K, Nagasawa K, Nakayama H, Dohmae N, Noguchi K, Noguchi T, Yohda M, Odaka M. Time-Resolved Crystallography of the Reaction Intermediate of Nitrile Hydratase: Revealing a Role for the Cysteinesulfenic Acid Ligand as a Catalytic Nucleophile. Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10763-7. doi: 10.1002/anie.201502731. PubMed PMID: 26333053.