KM11060

TargetMol
Product Code: TAR-T3135
Supplier: TargetMol
CodeSizePrice
TAR-T3135-5mg5mg£97.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3135-1mL1 mL * 10 mM (in DMSO)£99.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3135-10mg10mg£115.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3135-25mg25mg£168.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3135-50mg50mg£249.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3135-100mg100mg£389.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane.
CAS:
774549-97-2
Formula:
C19H17Cl2N3O2S
Molecular Weight:
422.32
Pathway:
Autophagy; Membrane transporter/Ion channel
Purity:
0.9967
SMILES:
Clc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12
Target:
CFTR; Autophagy

References

1. Robert R, et al. Mol Pharmacol. 2008 Feb;73(2):478-89. 2. Wu H, et al. PLoS One. 2014 Mar 26;9(3):e932003.