DN 1417
| Code | Size | Price |
|---|
| TAR-T31553-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
DN 1417 is an analog of thyrotropin releasing hormone.
CAS:
77026-81-4
Formula:
C22H29N5O12
Molecular Weight:
555.497
Purity:
0.98
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O.NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)C1CCC(=O)O1
References
1. Nakahara T, Matsumoto T, Hirano M, Uchimura H, Yokoo H, Nakamura K, Ishibashi K, Hirano H. Effect of DN-1417, a thyrotropin releasing hormone analog, on dopaminergic neurons in rat brain. Peptides. 1985 Nov-Dec;6(6):1093-9. PubMed PMID: 3938840.
2. Oshima I, Saito S, Shiota K, Miyake A, Oka Y, Nakayama R. Kinetic study on disappearance of gamma-butyrolactone-gamma-carbonyl-L-histidyl-L-prolinamide (DN-1417) from plasma using a radioimmunoassay for DN-1417 isobutylamide. J Pharmacobiodyn. 1983 Mar;6(3):202-8. PubMed PMID: 6410041.
3. Mori N, Fukatsu T. Anticonvulsant effect of DN-1417, a derivative of thyrotropin-releasing hormone, and liposome-entrapped DN-1417, on amygdaloid-kindled rats. Epilepsia. 1992 Nov-Dec;33(6):994-1000. PubMed PMID: 1464282.
4. Sakai S, Baba H, Sato M, Wada JA. Effect of DN-1417 on photosensitivity and cortically kindled seizure in Senegalese baboons, Papio papio. Epilepsia. 1991 Jan-Feb;32(1):16-21. PubMed PMID: 1898719.