Fce 21258
Code | Size | Price |
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TAR-T31751-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T31751-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T31751-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Fce 21258 is used to stimulate the adenylate cyclase of synovial fluid macrophages.
CAS:
71934-91-3
Formula:
C21H32O4
Molecular Weight:
348.48
Purity:
0.98
SMILES:
O=C(O)CCC/C=C1C[C@@]2([H])C[C@@H](O)[C@H](C#C[C@@H](O)CCCCC)[C@@]2([H])C1
References
1. Elliott GR, Swaak A, Bonta IL. The adenylate cyclase of rheumatoid synovial fluid macrophages is more sensitive for dl-5E, 19,14-di dehydro-carbo-prostacyclin, a stable prostacyclin analogue, than for prostaglandin E2. Prostaglandins Leukot Essent Fatty Acids. 1988 Aug;33(2):105-10. PubMed PMID: 2845436.
2. Adolfs MJ, Bonta IL. Plasticity of prostaglandin E2 receptor in human macrophages and the ternary complex of adenylate cyclase. Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:459-62. PubMed PMID: 2889337.
3. Adolfs MJ, Fieren MW, Bonta IL. Infectious-inflammatory changes in cyclic AMP levels and in their regulation by prostaglandins in human peritoneal macrophages. Prostaglandins Leukot Med. 1985 May;18(2):217-26. PubMed PMID: 2989936.
4. Morley J, Page CP, Paul W, Mongelli N, Ceserani R, Gandolfi C. A comparative study of PGI2 and two analogues (FCE 21292 and FCE 21258) in vitro and in vivo. Prostaglandins Leukot Med. 1983 Aug;11(4):391-9. PubMed PMID: 6353424.