FE-999024 free base
| Code | Size | Price |
|---|
| TAR-T31755-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31755-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31755-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
FE-999024 is a selective tissue kalkinase-like inhibitor that significantly inhibits plasma kalkinase-like activity in the pancreas.
CAS:
168825-65-8
Formula:
C26H31ClN6O2
Molecular Weight:
495.02
Purity:
0.98
SMILES:
N[C@H](Cc1ccc(Cl)cc1)C(=O)N(CCCNC(N)=N)[C@@H](Cc1cccc2ccccc12)C(N)=O
References
1. Broadley KJ, Blair AE, Kidd EJ, Bugert JJ, Ford WR. Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity. J Pharmacol Exp Ther. 2010 Dec;335(3):681-92. doi: 10.1124/jpet.110.171876. Epub 2010 Sep 16. PubMed PMID: 20847038.
2. Griesbacher T, Rainer I, Tiran B, Evans DM. Involvement of tissue kallikrein but not plasma kallikrein in the development of symptoms mediated by endogenous kinins in acute pancreatitis in rats. Br J Pharmacol. 2002 Nov;137(5):692-700. PubMed PMID: 12381683; PubMed Central PMCID: PMC1573532.
3. Wolf WC, Evans DM, Chao L, Chao J. A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness. Am J Pathol. 2001 Nov;159(5):1797-805. PubMed PMID: 11696440; PubMed Central PMCID: PMC1867063.