Fezelol
| Code | Size | Price |
|---|
| TAR-T31788-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Fezelol is a sesquiterpene coumarin isolated from the fruits of Ferula badrakema.
CAS:
51020-36-1
Formula:
C24H30O4
Molecular Weight:
382.5
Purity:
0.98
SMILES:
[H][C@@]12CC=C(C)[C@H](COc3ccc4ccc(=O)oc4c3)[C@@]1(C)CC[C@H](O)C2(C)C
References
1. Mollazadeh S, Matin MM, Bahrami AR, Iranshahi M, Behnam-Rassouli M, Rassouli FB, Neshati V. Feselol enhances the cytotoxicity and DNA damage induced by cisplatin in 5637 cells. Z Naturforsch C. 2011 Nov-Dec;66(11-12):555-61. PubMed PMID: 22351980.
2. Mollazadeh S, Matin MM, Iranshahi M, Bahrami AR, Neshati V, Behnam-Rassouli F. The enhancement of vincristine cytotoxicity by combination with feselol. J Asian Nat Prod Res. 2010 Jul;12(7):569-75. doi: 10.1080/10286020.2010.485565. PubMed PMID: 20628935.
3. Iranshahi M, Barthomeuf C, Bayet-Robert M, Chollet P, Davoodi D, Piacente S, Rezaee R, Sahebkar A. Drimane-Type Sesquiterpene Coumarins from Ferula gummosa Fruits Enhance Doxorubicin Uptake in Doxorubicin-Resistant Human Breast Cancer Cell Line. J Tradit Complement Med. 2014 Apr;4(2):118-25. doi: 10.4103/2225-4110.126181. PubMed PMID: 24860735; PubMed Central PMCID: PMC4003701.
4. Oughlissi-Dehak K, Lawton P, Michalet S, Bayet C, Darbour N, Hadj-Mahammed M, Badjah-Hadj-Ahmed YA, Dijoux-Franca MG, Guilet D. Sesquiterpenes from aerial parts of Ferula vesceritensis. Phytochemistry. 2008 Jun;69(9):1933-8. doi: 10.1016/j.phytochem.2008.03.010. Epub 2008 May 14. PubMed PMID: 18485426.