Fludalanine
| Code | Size | Price |
|---|
| TAR-T31813-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31813-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31813-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Fludalanine (MK641), an analogue of D-alanine, irreversiably inactivates racemase and also inhibits synthase. When used in combination with cycloserine, it has been found to be more active against a variety of non-mycobacterium organisms than fludalanine or cycloserine alone.
CAS:
35523-45-6
Formula:
C3H6FNO2
Molecular Weight:
108.091
Purity:
0.98
SMILES:
[2H][C@@](N)(CF)C(O)=O
References
1. Musson DG, Maglietto SM, Hwang SS, Gravellese D, Bayne WF. Simultaneous quantification of cycloserine and its prodrug acetylacetonylcycloserine in plasma and urine by high-performance liquid chromatography using ultraviolet absorbance and fluorescence after post-column derivatization. J Chromatogr. 1987 Feb 20;414(1):121-9. PubMed PMID: 3571377.
2. Darland GK, Hajdu R, Kropp H, Kahan FM, Walker RW, Vandenheuvel WJ. Oxidative and defluorinative metabolism of fludalanine, 2-2H-3-fluoro-D-alanine. Drug Metab Dispos. 1986 Nov-Dec;14(6):668-73. PubMed PMID: 2877824.
3. Dickinson JM, Mitchison DA. Activity of the combination of fludalanine and cycloserine against mycobacteria in vitro. Tubercle. 1985 Jun;66(2):109-15. PubMed PMID: 4024268.
4. Musson DG, Maglietto SM, Bayne WF. Determination of the antibiotic fludalanine in plasma and urine by high-performance liquid chromatography using a packed-bed, post-column reactor with o-phthalaldehyde and 2-mercaptoethanol. J Chromatogr. 1985 Mar 22;338(2):357-67. PubMed PMID: 3998023.