Folligen
| Code | Size | Price |
|---|
| TAR-T31842-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Folligen is a novel gonadotropin-releasing hormone analog against DMBA-induced tumours in the rat.
CAS:
103631-79-4
Formula:
C61H78N14O13
Molecular Weight:
1215.38
Purity:
0.98
SMILES:
CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CCC(=O)N1
References
1. Nicholson RI, K?ri G. Antitumour activity of folligen, a novel gonadotropin-releasing hormone analogue against DMBA-induced tumours in the rat. Tumour Biol. 1992;13(1-2):44-50. PubMed PMID: 1534181.
2. K?ri G, Balogh A, Sz?ke B, Tepl?n I, Csuka O. Gonadotropin-releasing hormone analogues inhibit cell proliferation and activate signal transduction pathways in MDA-MB-231 human breast cancer cell line. Tumour Biol. 1991;12(2):61-7. PubMed PMID: 1902971.
3. Tepl?n I. Peptides and antitumor activity. Development and investigation of some peptides with antitumor activity. Acta Biol Hung. 2000;51(1):1-29. Review. PubMed PMID: 10866357.
4. K?ri G, Balogh A, Horv?th A, Mez? I, Vad?sz Z, B?k?nyi G, Bajor T, V?ntus T, Tepl?n I, Horv?th J, et al. Novel antitumor peptide hormones and their effect on signal transduction. J Steroid Biochem Mol Biol. 1992 Sep;43(1-3):105-10. PubMed PMID: 1356011.