Fomocaine HCl
| Code | Size | Price |
|---|
| TAR-T31843-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31843-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31843-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Fomocaine is an type of anaesthetic agent blocking voltage-gated Na(+) currents in neurons.
CAS:
56583-43-8
Formula:
C20H26ClNO2
Molecular Weight:
347.88
Purity:
0.98
SMILES:
Cl.C(CN1CCOCC1)Cc1ccc(COc2ccccc2)cc1
References
1. Schoenberger M, Damijonaitis A, Zhang Z, Nagel D, Trauner D. Development of a new photochromic ion channel blocker via azologization of fomocaine. ACS Chem Neurosci. 2014 Jul 16;5(7):514-8. doi: 10.1021/cn500070w. Epub 2014 Jun 5. PubMed PMID: 24856540; PubMed Central PMCID: PMC4102962.
2. Baumgart M, Feller C, Natura G, Dahse T, Schaible HG, Dahse I. Blockade of TTX-resistant and TTX-sensitive Na+ currents in cultured dorsal root ganglion neurons by fomocaine and the fomocaine derivative Oe 9000. Brain Res. 2010 Oct 28;1358:54-63. doi: 10.1016/j.brainres.2010.08.033. Epub 2010 Aug 19. PubMed PMID: 20727863.
3. Lupp A, Karge E, Dahse T, Glassl P, Jung B, Listing M, Seeling A, Wange J, Wennek-Klose J, Oelschl?ger H, Fleck C. A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--Part III. Arzneimittelforschung. 2007;57(11):685-8. doi: 10.1055/s-0031-1296668. Review. PubMed PMID: 18193689.
4. Lupp A, Karge E, Dahse T, Glassl P, Jung B, Listing M, Seeling A, Wange J, Wennek-Klose J, Oelschl?ger H, Fleck C. A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--part II. Arzneimittelforschung. 2007;57(10):633-40. PubMed PMID: 18074756.