Gantacurium chloride
| Code | Size | Price |
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| TAR-T31914-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Gantacurium chloride is a benzylisoquinoline alkaloid, which may be used as an adjuvant in anesthesia.
CAS:
213998-46-0
Formula:
C53H69Cl3N2O14
Molecular Weight:
1064.49
Purity:
0.98
SMILES:
[Cl-].[Cl-].COc1cc2CC[N@@+](C)(CCCOC(=O)C(Cl)=CC(=O)OCCC[N@@+]3(C)CCc4cc(OC)c(OC)cc4[C@@H]3c3cc(OC)c(OC)c(OC)c3)[C@H](Cc3cc(OC)c(OC)c(OC)c3)c2cc1OC
References
1. Martin-Flores M, Cheetham J, Campoy L, Sakai DM, Heerdt PM, Gleed RD. Effect of gantacurium on evoked laryngospasm and duration of apnea in anesthetized healthy cats. Am J Vet Res. 2015 Mar;76(3):216-23. doi: 10.2460/ajvr.76.3.216. PubMed PMID: 25710757.
2. Sunaga H, Zhang Y, Savarese JJ, Emala CW. Gantacurium and CW002 do not potentiate muscarinic receptor-mediated airway smooth muscle constriction in guinea pigs. Anesthesiology. 2010 Apr;112(4):892-9. doi: 10.1097/ALN.0b013e3181d32016. PubMed PMID: 20216393; PubMed Central PMCID: PMC2854830.
3. Savarese JJ, McGilvra JD, Sunaga H, Belmont MR, Van Ornum SG, Savard PM, Heerdt PM. Rapid chemical antagonism of neuromuscular blockade by L-cysteine adduction to and inactivation of the olefinic (double-bonded) isoquinolinium diester compounds gantacurium (AV430A), CW 002, and CW 011. Anesthesiology. 2010 Jul;113(1):58-73. doi: 10.1097/ALN.0b013e3181dc1b5b. PubMed PMID: 20526187.
4. Naguib M, Brull SJ. Update on neuromuscular pharmacology. Curr Opin Anaesthesiol. 2009 Aug;22(4):483-90. doi: 10.1097/ACO.0b013e32832b8cff. Review. PubMed PMID: 19384229.