GYKI-13324
| Code | Size | Price |
|---|
| TAR-T32026-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. GYKI-13324 was studied on human colorectal tumor xenograft lines. Given orally in single or multiple daily doses, GYKI-13324 produced long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, with slightly lower toxicity than that of BCNU, seems to be a candidate in the clinical management of colorectal tumors.
CAS:
76123-41-6
Formula:
C10H18Cl2N6O6
Molecular Weight:
389.19
Purity:
0.98
SMILES:
OC(CNC(=O)N(CCCl)N=O)C(O)CN(N=O)C(=O)NCCCl
References
1. P?l K, Kopper L, Lapis K. Chemotherapeutic sensitivity of liver metastases from intrasplenically-growing Lewis lung tumor. Clin Exp Metastasis. 1983 Oct-Dec;1(4):341-7. PubMed PMID: 6443744.
2. Kopper L, Lapis K, Cs?nyi E, Horv?th T. Effect of a new bifunctional nitrosoureido derivative on human colorectal tumor xenografts. Anticancer Res. 1981;1(4):229-33. PubMed PMID: 7345967.
3. Cs?nyi E, Horv?th T, Kir?ly E, Lapis K, Kopper L. New type bifunctional nitrosoureido derivatives with cytostatic activity. Oncology. 1980;37 Suppl 1:59-66. PubMed PMID: 7454201.