Hemigossypol
| Code | Size | Price |
|---|
| TAR-T32056-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Hemigossypol is a precursor of gossypol biosynthesis.
CAS:
40817-07-0
Formula:
C15H16O4
Molecular Weight:
260.289
Purity:
0.98
SMILES:
CC(C)c1c(O)c(O)c(C=O)c2c(O)cc(C)cc12
References
1. Effenberger I, Harport M, Pfannstiel J, Klaiber I, Schaller A. Expression in Pichia pastoris and characterization of two novel dirigent proteins for atropselective formation of gossypol. Appl Microbiol Biotechnol. 2017 Mar;101(5):2021-2032. doi: 10.1007/s00253-016-7997-3. Epub 2016 Nov 17. PubMed PMID: 27858135.
2. Effenberger I, Zhang B, Li L, Wang Q, Liu Y, Klaiber I, Pfannstiel J, Wang Q, Schaller A. Dirigent Proteins from Cotton (Gossypium sp.) for the Atropselective Synthesis of Gossypol. Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14660-3. doi: 10.1002/anie.201507543. Epub 2015 Oct 13. PubMed PMID: 26460165.
3. Wagner TA, Liu J, Puckhaber LS, Bell AA, Williams H, Stipanovic RD. RNAi construct of a cytochrome P450 gene CYP82D109 blocks an early step in the biosynthesis of hemigossypolone and gossypol in transgenic cotton plants. Phytochemistry. 2015 Jul;115:59-69. doi: 10.1016/j.phytochem.2015.02.016. Epub 2015 Mar 17. PubMed PMID: 25794893.
4. Megnassan E, Keita M, Bieri C, Esmel A, Frecer V, Miertus S. Design of novel dihydroxynaphthoic acid inhibitors of Plasmodium falciparum lactate dehydrogenase. Med Chem. 2012 Sep;8(5):970-84. PubMed PMID: 22741776.