Histidylprolineamide
| Code | Size | Price |
|---|
| TAR-T32083-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Histidylprolineamide is the N-terminal of TRH.
CAS:
33605-69-5
Formula:
C11H17N5O2
Molecular Weight:
251.29
Purity:
0.98
SMILES:
N[C@@H](Cc1c[nH]cn1)C(=O)N1CCCC1C(N)=O
References
1. O'Connor B, O'Cuinn G. Post-proline dipeptidyl-aminopeptidase from synaptosomal membranes of guinea-pig brain. A possible role for this activity in the hydrolysis of His-ProNH2, arising from the action of synaptosomal membrane pyroglutamate aminopeptidase on thyroliberin. Eur J Biochem. 1986 Jan 15;154(2):329-35. PubMed PMID: 2867901.
2. Browne P, O'Cuinn G. An evaluation of the role of a pyroglutamyl peptidase, a post-proline cleaving enzyme and a post-proline dipeptidyl amino peptidase, each purified from the soluble fraction of guinea-pig brain, in the degradation of thyroliberin in vitro. Eur J Biochem. 1983 Dec 1;137(1-2):75-87. PubMed PMID: 6140164.
3. Matsui T, Prasad C, Peterkofsky A. Metabolism of thyrotropin releasing hormone in brain extracts. Isolation and characterization of an imidopeptidase for histidylprolineamide. J Biol Chem. 1979 Apr 10;254(7):2439-45. PubMed PMID: 107159.