Iduronate 2-sulfate
| Code | Size | Price |
|---|
| TAR-T32138-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Iduronate 2-sulfate is a sulfatase enzyme related to Hunter syndrome.
CAS:
89846-17-3
Formula:
C6H10O10S
Molecular Weight:
274.2
Purity:
0.98
SMILES:
O[C@@H]([C@H](O)[C@@H](OS(O)(=O)=O)C=O)[C@@H](O)C(O)=O
References
1. Alm?ciga-D?az CJ, Tolosa-D?az AD, Pimentel LN, Bonilla YA, Rodr?guez-L?pez A, Espejo-Mojica AJ, Pati?o JD, S?nchez OF, Gonzalez-Santos J. Anaerobic sulfatase maturase AslB from Escherichia coli activates human recombinant iduronate-2-sulfate sulfatase (IDS) and N-acetylgalactosamine-6-sulfate sulfatase (GALNS). Gene. 2017 Nov 15;634:53-61. doi: 10.1016/j.gene.2017.08.043. Epub 2017 Sep 4. PubMed PMID: 28882567.
2. Chung JK, Brown E, Crooker B, Palmieri KJ, McCauley TG. Biodistribution of Idursulfase Formulated for Intrathecal Use (Idursulfase-IT) in Cynomolgus Monkeys after Intrathecal Lumbar Administration. PLoS One. 2016 Oct 20;11(10):e0164765. doi: 10.1371/journal.pone.0164765. eCollection 2016. PubMed PMID: 27764180; PubMed Central PMCID: PMC5072681.
3. Morales-?lvarez ED, Rivera-Hoyos CM, Land?zuri P, Poutou-Pi?ales RA, Pedroza-Rodr?guez AM. Bioinformatic Analysis of the Human Recombinant Iduronate 2-Sulfate Sulfatase. Open Microbiol J. 2016 May 31;10:124-32. doi: 10.2174/1874285801610010124. eCollection 2016. PubMed PMID: 27335624; PubMed Central PMCID: PMC4899537.
4. Prasad C, Rupar CA, Campbell C, Napier M, Ramsay D, Tay KY, Sharan S, Prasad AN. Case of multiple sulfatase deficiency and ocular albinism: a diagnostic odyssey. Can J Neurol Sci. 2014 Sep;41(5):626-31. doi: 10.1017/cjn.2014.12. PubMed PMID: 25373814.