Imagabalin
| Code | Size | Price |
|---|
| TAR-T32143-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32143-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32143-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Imagabalin ( PD0332334, PF-00195889) is a drug that acts as a ligand for the α2δ1 subunit of the voltage-dependent calcium channel with higher selectivity than α2δ2. Imagabalin has shown preclinical efficacy with anti-anxiety, analgesic, hypnotic, and anticonvulsant activity.
CAS:
610300-07-7
Formula:
C9H19NO2
Molecular Weight:
173.256
Purity:
0.98
SMILES:
CCC[C@@H](C)C[C@H](N)CC(O)=O
References
1. Dunn AL, Codina A, Foley DA, Marquez BL, Zell MT. A detailed mechanistic investigation into the reaction of 3-methylpentanoic acid with Meldrum's acid utilizing online NMR spectroscopy. Magn Reson Chem. 2015 Aug 31. doi: 10.1002/mrc.4317. [Epub ahead of print] PubMed PMID: 26332370.
2. Midelfort KS, Kumar R, Han S, Karmilowicz MJ, McConnell K, Gehlhaar DK, Mistry A, Chang JS, Anderson M, Villalobos A, Minshull J, Govindarajan S, Wong JW. Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. Protein Eng Des Sel. 2013 Jan;26(1):25-33. doi: 10.1093/protein/gzs065. Epub 2012 Sep 25. PubMed PMID: 23012440.