IMC-48
| Code | Size | Price |
|---|
| TAR-T32146-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32146-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32146-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
IMC-48, as a BCL2 i-motif-interactive compound, can act by stabilizing or facilitating the folding of the i-motif.
CAS:
106068-99-9
Formula:
C35H63IN2O
Molecular Weight:
654.806
Purity:
0.98
SMILES:
[I-].CC(C)CCCC(C)C1CCC2C3CCC4CC(CCC4(C)C3CCC12C)NC(=O)C[N+]1(C)CCCCC1
References
1. Fernandez M, Toimil RF, Rasslan Z, Ilias EJ, Gradinar AL, Malheiros CA. ASSESSMENT OF BODY FAT IN OBESE PATIENTS PREOPERATIVELY FOR BARIATRIC SURGERY. Arq Bras Cir Dig. 2016;29Suppl 1(Suppl 1):59-61. doi: 10.1590/0102-6720201600S10015. English, Portuguese. PubMed PMID: 27683778; PubMed Central PMCID: PMC5064249.
2. Cui Y, Koirala D, Kang H, Dhakal S, Yangyuoru P, Hurley LH, Mao H. Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL. Nucleic Acids Res. 2014 May;42(9):5755-64. doi: 10.1093/nar/gku185. Epub 2014 Mar 7. PubMed PMID: 24609386; PubMed Central PMCID: PMC4027204.
3. Kang HJ, Kendrick S, Hecht SM, Hurley LH. The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules. J Am Chem Soc. 2014 Mar 19;136(11):4172-85. doi: 10.1021/ja4109352. Epub 2014 Mar 7. PubMed PMID: 24559432; PubMed Central PMCID: PMC3985447.