Retrorsine N-oxide
| Code | Size | Price |
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| TAR-T32198-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Isatidine is a pyrrolizidine alkaoid.
CAS:
15503-86-3
Formula:
C18H23NO7
Molecular Weight:
365.382
Purity:
0.98
SMILES:
[H][C@]12OC(=O)C(C[C@@H](C)[C@](O)(CO)C(=O)OCC3=CCN(CC1=O)[C@@]23[H])=C/C
References
1. Kevekordes S, Spielberger J, Burghaus CM, Birkenkamp P, Zietz B, Paufler P, Diez M, Bolten C, Dunkelberg H. Micronucleus formation in human lymphocytes and in the metabolically competent human hepatoma cell line Hep-G2: results with 15 naturally occurring substances. Anticancer Res. 2001 Jan-Feb;21(1A):461-9. PubMed PMID: 11299780.
2. M?ller L, Kasper P, Kaufmann G. The clastogenic potential in vitro of pyrrolizidine alkaloids employing hepatocyte metabolism. Mutat Res. 1992 Jul;282(3):169-76. PubMed PMID: 1378549.
3. Isatidine. IARC Monogr Eval Carcinog Risk Chem Man. 1976;10:269-73. Review. PubMed PMID: 186388.
4. SCHOENTAL R, HEAD MA, PEACOCK PR. Senecio alkaloids; primary liver tumours in rats as a result of treatment with (1) a mixture of alkaloids from S. jacobaea Lin.; (2) retrorsine; (3) isatidine. Br J Cancer. 1954 Sep;8(3):458-65. PubMed PMID: 13230379; PubMed Central PMCID: PMC2007966.