Jaspisamide A
| Code | Size | Price |
|---|
| TAR-T32270-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Jaspisamide A is an type of actin-binding protein.
CAS:
149420-76-8
Formula:
C45H62N4O12
Molecular Weight:
851.007
Purity:
0.98
SMILES:
COC(CC1OC(=O)CC(O)CC=C/C(=O)C(C)C(OC)c2coc(n2)-c2coc(n2)-c2coc(C=C/CCC1C)n2)C(C)CCC(=O)C(C)C(OC)C(C)C=CN(C)C=O
References
1. Tanaka J, Yan Y, Choi J, Bai J, Klenchin VA, Rayment I, Marriott G. Biomolecular mimicry in the actin cytoskeleton: mechanisms underlying the cytotoxicity of kabiramide C and related macrolides. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13851-6. Epub 2003 Nov 11. PubMed PMID: 14612571; PubMed Central PMCID: PMC283510.
2. Klenchin VA, Allingham JS, King R, Tanaka J, Marriott G, Rayment I. Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin. Nat Struct Biol. 2003 Dec;10(12):1058-63. Epub 2003 Oct 26. PubMed PMID: 14578936.
3. Kobayashi J, Murata O, Shigemori H. Jaspisamides A-C, new cytotoxic macrolides from the Okinawan sponge Jaspis sp. J Nat Prod. 1993 May;56(5):787-91. PubMed PMID: 8326327.