Jatrophatrione
| Code | Size | Price |
|---|
| TAR-T32273-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Jatrophatrione is a type of bioactive mesotricyclic diterpenoid.
CAS:
58298-76-3
Formula:
C20H26O3
Molecular Weight:
314.425
Purity:
0.98
SMILES:
[H][C@]12C[C@@H](C)C=C1C=C(C)/C(=O)C[C@]1([H])C(C)(C)CC(=O)[C@@]1(C)C2=O
References
1. Melchor-Mart?nez EM, Silva-Mares DA, Torres-L?pez E, Waksman-Minsky N, Pauli GF, Chen SN, Niemitz M, S?nchez-Castellanos M, Toscano A, Cuevas G, Rivas-Galindo VM. Stereochemistry of a Second Riolozane and Other Diterpenoids from Jatropha dioica. J Nat Prod. 2017 Aug 25;80(8):2252-2262. doi: 10.1021/acs.jnatprod.7b00193. Epub 2017 Aug 3. PubMed PMID: 28771358; PubMed Central PMCID: PMC5714812.
2. Yang J, Long YO, Paquette LA. Concise total syntheses of the bioactive mesotricyclic diterpenoids jatrophatrione and citlalitrione. J Am Chem Soc. 2003 Feb 12;125(6):1567-74. PubMed PMID: 12568617.
3. Paquette LA, Yang J, Long YO. Concerning the antileukemic agent jatrophatrione: the first total synthesis of a [5.9.5] tricyclic diterpene. J Am Chem Soc. 2002 Jun 12;124(23):6542-3. PubMed PMID: 12047168.
4. Paquette LA, Edmondson SD, Monck N, Rogers RD. Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 2. Functionalization of Advanced Polycyclic Precursors to the 9-Epi and 8,9-Dehydro Congeners. J Org Chem. 1999 Apr 30;64(9):3255-3265. PubMed PMID: 11674428.