Jmv 180
| Code | Size | Price |
|---|
| TAR-T32297-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Jmv 180, a CCK analog, can distinguish high-affinity cholecystokinin receptors from low-affinity cholecystokinin receptors.
CAS:
119733-42-5
Formula:
C55H72N8O18S
Molecular Weight:
1165.28
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OS(O)(=O)=O)cc1)C(=O)NCCCCCC(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)OCCc1ccccc1
References
1. Alexandre M, Uduman AK, Minervini S, Raoof A, Shugrue CA, Akinbiyi EO, Patel V, Shitia M, Kolodecik TR, Patton R, Gorelick FS, Thrower EC. Tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone initiates and enhances pancreatitis responses. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 15;303(6):G696-704. doi: 10.1152/ajpgi.00138.2012. Epub 2012 Jul 26. PubMed PMID: 22837343; PubMed Central PMCID: PMC3468532.
2. Kinch DC, Peters JH, Simasko SM. Comparative pharmacology of cholecystokinin induced activation of cultured vagal afferent neurons from rats and mice. PLoS One. 2012;7(4):e34755. doi: 10.1371/journal.pone.0034755. Epub 2012 Apr 13. PubMed PMID: 22514663; PubMed Central PMCID: PMC3326049.
3. Staljanssens D, De Vos WH, Willems P, Van Camp J, Smagghe G. Time-resolved quantitative analysis of CCK1 receptor-induced intracellular calcium increase. Peptides. 2012 Mar;34(1):219-25. doi: 10.1016/j.peptides.2011.02.014. Epub 2011 Feb 23. PubMed PMID: 21352882.
4. Li Y, Wu X, Zhou S, Owyang C. Low-affinity CCK-A receptors are coexpressed with leptin receptors in rat nodose ganglia: implications for leptin as a regulator of short-term satiety. Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G217-27. doi: 10.1152/ajpgi.00356.2010. Epub 2010 Nov 25. PubMed PMID: 21109591; PubMed Central PMCID: PMC3043649.