Julocrotine
| Code | Size | Price |
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| TAR-T32320-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Julocrotine is a type of glutarimide alkaloid from Croton membranaceus.
CAS:
492-87-5
Formula:
C18H24N2O3
Molecular Weight:
316.401
Purity:
0.98
SMILES:
CC[C@H](C)C(=O)N[C@H]1CCC(=O)N(CCc2ccccc2)C1=O
References
1. Ndunda B, Langat MK, Wanjohi JM, Midiwo JO, Kerubo LO. Alienusolin, a new 4?-deoxyphorbol ester derivative, and crotonimide C, a new glutarimide alkaloid from the Kenyan Croton alienus. Planta Med. 2013 Dec;79(18):1762-6. doi: 10.1055/s-0033-1351044. Epub 2013 Dec 19. PubMed PMID: 24356872.
2. Neves Filho RA, Westermann B, Wessjohann LA. Synthesis of (-)-julocrotine and a diversity oriented Ugi-approach to analogues and probes. Beilstein J Org Chem. 2011;7:1504-7. doi: 10.3762/bjoc.7.175. Epub 2011 Nov 7. PubMed PMID: 22238524; PubMed Central PMCID: PMC3252850.
3. Silva LL, Joussef AC. Synthesis of N-[(3S)-2,6-dioxo-1-(2-phenylethyl)-3-piperidinyl]-(2S)-2-methylbutanamide ((-)-julocrotine). J Nat Prod. 2011 Jun 24;74(6):1531-4. doi: 10.1021/np200234e. Epub 2011 May 5. PubMed PMID: 21545108.
4. Guimar?es LR, Rodrigues AP, Marinho PS, Muller AH, Guilhon GM, Santos LS, do Nascimento JL, Silva EO. Activity of the julocrotine, a glutarimide alkaloid from Croton pullei var. glabrior, on Leishmania (L.) amazonensis. Parasitol Res. 2010 Oct;107(5):1075-81. doi: 10.1007/s00436-010-1973-0. Epub 2010 Jul 27. PubMed PMID: 20661748.