Kidamycin
| Code | Size | Price |
|---|
| TAR-T32395-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Kidamycin, obtained from Streptomyces phaeoverticillatus strains, can interfere with RNA synthesis.
CAS:
11072-82-5
Formula:
C39H48N2O9
Molecular Weight:
688.818
Purity:
0.98
SMILES:
CC=C(C)c1cc(=O)c2c(C)cc3C(=O)c4c(cc(C5CC(C)(C(O)C(C)O5)N(C)C)c(O)c4C(=O)c3c2o1)C1CC(C(O)C(C)O1)N(C)C
References
1. Fei Z, McDonald FE. Stereo- and regioselective glycosylations to the bis-C-arylglycoside of kidamycin. Org Lett. 2007 Aug 30;9(18):3547-50. Epub 2007 Aug 11. PubMed PMID: 17691798; PubMed Central PMCID: PMC4604443.
2. Fei Z, McDonald FE. Synthesis of the aglycones of altromycins and kidamycin from a common intermediate. Org Lett. 2005 Aug 18;7(17):3617-20. PubMed PMID: 16092833; PubMed Central PMCID: PMC1388187.
3. Takeshima H, Okamoto M, Komiyama K, Umezawa I. Mechanism of action of acetyl kidamycin. I. Interaction with DNA. Biochim Biophys Acta. 1976 Jan 5;418(1):24-8. PubMed PMID: 942683.
4. Umezawa I, Komiyama K, Takeshima H, Hata T, Kono M. A new antitumor antibiotic, kidamycin. IV. Pharmacokinetics of acetyl-kidamycin. J Antibiot (Tokyo). 1973 Nov;26(11):669-75. PubMed PMID: 4792114.