Kobusine
| Code | Size | Price |
|---|
| TAR-T32409-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Kobusine is an aconite alkaloid of the C20-diterpenoid type.
CAS:
27530-78-5
Formula:
C20H27NO2
Molecular Weight:
313.441
Purity:
0.98
SMILES:
C[C@]12CN3[C@@H]4C[C@@]56[C@@H]7C[C@H]([C@H](O)[C@H]5[C@](CCC1)([C@@H]37)[C@H]24)C(=C)[C@H]6O
References
1. Wada K, Ishizuki S, Mori T, Fujihira E, Kawahara N. Effects of Aconitum alkaloid kobusine and pseudokobusine derivatives on cutaneous blood flow in mice. Biol Pharm Bull. 1998 Feb;21(2):140-6. PubMed PMID: 9514608.
2. Wada K, Ishizuki S, Mori T, Fujihira E, Kawahara N. Effects of Aconitum alkaloid kobusine and pseudokobusine derivatives on cutaneous blood flow in mice; II. Biol Pharm Bull. 2000 May;23(5):607-15. PubMed PMID: 10823674.
3. OKAMOTO T, NATSUME M, ZENDA H, KAMATA S. Structural correlation of kobusine to pseudokobusine. Chem Pharm Bull (Tokyo). 1962 Sep;10:883-6. PubMed PMID: 13939783.
4. Wada K, Ohkoshi E, Zhao Y, Goto M, Morris-Natschke SL, Lee KH. Evaluation of Aconitum diterpenoid alkaloids as antiproliferative agents. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1525-31. doi: 10.1016/j.bmcl.2015.02.018. Epub 2015 Feb 18. PubMed PMID: 25770782; PubMed Central PMCID: PMC4374035.