L 683519
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
L 683519 is one of the Tacrolimus impurities with immunosuppressant and could restrain the activity of FK-506 binding protein.
CAS:
132172-14-6
Formula:
C43H67NO12
Molecular Weight:
790.004
Purity:
0.98
SMILES:
[H][C@@]12C[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@H]([C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)C=C(C)C[C@H](C)C[C@H](OC)[C@H]2O)C(C)=C[C@@H]1CCC(O)C(C1)OC
References
1. Chen TS, Arison BH, Wicker LS, Inamine ES. Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. J Antibiot (Tokyo). 1992 Apr;45(4):577-80. Erratum in: J Antibiot (Tokyo) 1992 Jun;45(6):C-2. PubMed PMID: 1375593.