L 693989
| Code | Size | Price |
|---|
| TAR-T32470-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
L 693989 is a pneumocandin.
CAS:
138661-20-8
Formula:
C50H80N8NaO20P
Molecular Weight:
1167.19
Purity:
0.98
SMILES:
[Na+].CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(O)C(O)NC(=O)C2C(O)CCN2C(=O)C(NC(=O)C(NC(=O)C2CC(O)CN2C(=O)C(NC1=O)C(C)O)C(O)C(O)c1ccc(OP(O)([O-])=O)cc1)C(O)CC(N)=O
References
1. Flattery AM, Abruzzo GK, Gill CJ, Smith JG, Bartizal K. New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents. Antimicrob Agents Chemother. 1996 Jul;40(7):1604-9. PubMed PMID: 8807048; PubMed Central PMCID: PMC163381.
2. Kurtz MB, Bernard EM, Edwards FF, Marrinan JA, Dropinski J, Douglas CM, Armstrong D. Aerosol and parenteral pneumocandins are effective in a rat model of pulmonary aspergillosis. Antimicrob Agents Chemother. 1995 Aug;39(8):1784-9. PubMed PMID: 7486919; PubMed Central PMCID: PMC162826.
3. Schmatz DM, Powles MA, McFadden D, Nollstadt K, Bouffard FA, Dropinski JF, Liberator P, Andersen J. New semisynthetic pneumocandins with improved efficacies against Pneumocystis carinii in the rat. Antimicrob Agents Chemother. 1995 Jun;39(6):1320-3. PubMed PMID: 7574523; PubMed Central PMCID: PMC162734.
4. Powles MA, McFadden DC, Liberator PA, Anderson JW, Vadas EB, Meisner D, Schmatz DM. Aerosolized L-693,989 for Pneumocystis carinii prophylaxis in rats. Antimicrob Agents Chemother. 1994 Jun;38(6):1397-401. PubMed PMID: 8092844; PubMed Central PMCID: PMC188217.