Lemuteporfin
Code | Size | Price |
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TAR-T32632-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Lemuteporfin, also known DRM05, QLT-0074 , is a diester derivative of benzoporphyrin derivative, is a neutral, uncharged benzoporphyrin molecule having symmetrical diethylene glycol groups; this maintains its amphiphilic character. It differs from another benzoporphyrin derivative, verteporfin, as it is a single regioisomer. verteporfin, consists of two regioisomers present in equal proportions and is negatively charged at neutral pH.
CAS:
215808-49-4
Formula:
C44H48N4O10
Molecular Weight:
792.886
Purity:
0.98
SMILES:
COC(=O)[C@@H]1C(=CC=C2c3cc4[nH]c(cc5nc(cc6[nH]c(cc(n3)[C@]12C)c(C)c6CCC(=O)OCCO)c(CCC(=O)OCCO)c5C)c(C=C)c4C)C(=O)OC
References
1. Surface topographies for non-toxic bioadhesion control By Brennan, Anthony B.; Long, Christopher James; Bagan, Joseph W.; Schumacher, James Frederick; Spiecker, Mark M. From U.S. Pat. Appl. Publ. (2010), US 20100226943 A1 20100909.
2. Combination of photodynamic therapy and anti-vegf agents in the treatment of unwanted choroidal neovasculature By Strong, Andrew; Hao, Yong From PCT Int. Appl. (2010), WO 2010069073 A1 20100624.
3. Photodynamic therapy of sebaceous gland disorders By Tao, Jing-Song; Curaudeau, Alain H.; Hunt, David; Boniface, Graham; Rubinachik, Valery From PCT Int. Appl. (2009), WO 2009093144 A2 20090730.
4. Photodynamic therapy for the treatment of hidradenitis suppurativa By Tao, Jing-Song; Hunt, David W. C. From PCT Int. Appl. (2008), WO 2008052350 A1 20080508.