Lerimazoline

TargetMol
Product Code: TAR-T32656
Supplier: TargetMol
CodeSizePrice
TAR-T32656-5mg5mg£850.00
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Quantity:
TAR-T32656-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T32656-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Lerimazoline(Trimazoline, Trimizoline, ST-71) is used in the form of tramazoline hydrochloride in nasal decongestant preparations. It is used to inhibits the secretion of nasal mucus as an α-adrenergic receptor agonist.
CAS:
54765-26-3
Formula:
C13H18N2
Molecular Weight:
202.301
Purity:
0.98
SMILES:
Cc1cc(C)c(CC2=NCCN2)c(C)c1

References

1. Katona G, Sult?sz M, Farkas Z, Gyimesi A, Hirschberg A, Huszka J, Radv?nszky F, Simon ?, F?l?p G, L?ng J, Ablonczy M, Nirnberger G, Holm C. Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils: a multicenter, uncontrolled, observational trial. Clin Transl Allergy. 2015 Nov 4;5:38. doi: 10.1186/s13601-015-0084-5. eCollection 2015. PubMed PMID: 26539289; PubMed Central PMCID: PMC4632331. 2. Zhang JX, Li ZY, Zhao L, Li G, Cao GL, Zhang CY. A Prospective Randomized Trial to Compare the Efficacy of Tramazoline and Cocaine for Nasal Vasoconstriction before Nasal Surgery. Drug Res (Stuttg). 2015 Dec;65(12):672. doi: 10.1055/s-0034-1387769. Epub 2014 Sep 4. PubMed PMID: 25188610. 3. Koutsourelakis I, Minaritzoglou A, Zakynthinos G, Vagiakis E, Zakynthinos S. The effect of nasal tramazoline with dexamethasone in obstructive sleep apnoea patients. Eur Respir J. 2013 Oct;42(4):1055-63. doi: 10.1183/09031936.00142312. Epub 2013 Feb 8. PubMed PMID: 23397296. 4. Antoniou CG, Markopoulou CK, Kouskoura MG, Koundourellis JE. Study and development of reversed-phase HPLC systems for the determination of 2-imidazolines in the presence of preservatives in pharmaceutical preparations. J AOAC Int. 2011 May-Jun;94(3):703-12. PubMed PMID: 21796997.