Linsidomine
| Code | Size | Price |
|---|
| TAR-T32770-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lincydomine is a smooth muscle relaxant, beneficial to the treatment of unstable angina pectoris, but also can open the respiratory tract of humans and guinea pigs.
CAS:
33876-97-0
Formula:
C6H10N4O2
Molecular Weight:
170.172
Purity:
0.98
SMILES:
[NH-]c1c[n+](no1)N1CCOCC1
References
1. Sutherland FC, de Jager AD, Swart KJ, Hundt HK, Scanes T, Hundt AF. Determination of linsidomine in human plasma by tandem LC-MS with ESI. J Pharm Biomed Anal. 2000 Apr;22(3):461-7. PubMed PMID: 10766363.
2. Spreux-Varoquaux O, Doll J, Dutot C, Grandjean N, Cordonnier P, Pays M, Andrieu J, Advenier C. Pharmacokinetics of molsidomine and its active metabolite, linsidomine, in patients with liver cirrhosis. Br J Clin Pharmacol. 1991 Sep;32(3):399-401. PubMed PMID: 1777378; PubMed Central PMCID: PMC1368538.
3. Stief CG, Holmquist F, Djamilian M, Krah H, Andersson KE, Jonas U. Preliminary results with the nitric oxide donor linsidomine chlorhydrate in the treatment of human erectile dysfunction. J Urol. 1992 Nov;148(5):1437-40. PubMed PMID: 1433545.
4. Prast H, Lamberti C, Fischer H, Tran MH, Philippu A. Nitric oxide influences the release of histamine and glutamate in the rat hypothalamus. Naunyn Schmiedebergs Arch Pharmacol. 1996 Dec;354(6):731-5. PubMed PMID: 8971733.