Luminamicin
| Code | Size | Price |
|---|
| TAR-T32949-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Luminamicin is active against anaerobic bacteria, especially Clostridium sp.; isolated from actinomycete strain OMR-59.
CAS:
99820-21-0
Formula:
C32H43O12
Molecular Weight:
619.684
Purity:
0.98
SMILES:
COC1C2CCC[O]3CC4OC(C)=CCC5=C(C[O](=O)C5)CC(=O)OC(=O)CC5=C4C(C)C(O)C23C(CC1=O)C(O)CCO5
References
1. Ando H, Kimishima A, Ohara M, Hirose T, Matsumaru T, Takada H, Morodome K, Miyamoto T, Sugawara A, ?mura S, Sunazuka T. Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety. J Antibiot (Tokyo). 2018 Feb;71(2):268-272. doi: 10.1038/ja.2017.77. Epub 2017 Jul 5. PubMed PMID: 28676718.
2. Gouda H, Sunazuka T, Ui H, Handa M, Sakoh Y, Iwai Y, Hirono S, Omura S. Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher method. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18286-91. Epub 2005 Dec 12. PubMed PMID: 16344486; PubMed Central PMCID: PMC1317948.
3. Rasmussen RR, Scherr MH, Whittern DN, Buko AM, McAlpine JB. Coloradocin, an antibiotic from a new Actinoplanes. II. Identity with luminamicin and elucidation of structure. J Antibiot (Tokyo). 1987 Oct;40(10):1383-93. PubMed PMID: 3680004.
4. Jackson M, Karwowski JP, Theriault RJ, Fernandes PB, Semon RC, Kohl WL. Coloradocin, an antibiotic from a new Actinoplanes. I. Taxonomy, fermentation and biological properties. J Antibiot (Tokyo). 1987 Oct;40(10):1375-82. PubMed PMID: 3680003.