LY 175877
| Code | Size | Price |
|---|
| TAR-T32991-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
LY 175877 is a bioactive chemical.
CAS:
98524-57-3
Formula:
C14H22N4
Molecular Weight:
246.358
Purity:
0.98
SMILES:
[H][C@@]12CCCN(CCC)[C@@]1([H])Cc1cnc(N)nc1C2
References
1. Tsuchioka A, Oana F, Suzuki T, Yamauchi Y, Ijiro T, Kaidoh K, Hiratochi M. Duration of drug action of dopamine D2 agonists in mice with 6-hydroxydopamine-induced lesions. Neuroreport. 2015 Dec 16;26(18):1126-32. doi: 10.1097/WNR.0000000000000484. PubMed PMID: 26559726.
2. Ponce G, Qui?ones-Lombra?a A, Mart?n-Palanco NG, Rubio-Solsona E, Jim?nez-Arriero M?, Palomo T, Hoenicka J. The Addiction-Related Gene Ankk1 is Oppositely Regulated by D1R- and D2R-Like Dopamine Receptors. Neurotox Res. 2016 Apr;29(3):345-50. doi: 10.1007/s12640-015-9545-9. Epub 2015 Jul 21. PubMed PMID: 26194616.
3. Chen YW, Morganstern I, Barson JR, Hoebel BG, Leibowitz SF. Differential role of D1 and D2 receptors in the perifornical lateral hypothalamus in controlling ethanol drinking and food intake: possible interaction with local orexin neurons. Alcohol Clin Exp Res. 2014 Mar;38(3):777-86. doi: 10.1111/acer.12313. Epub 2013 Nov 15. PubMed PMID: 24236888; PubMed Central PMCID: PMC4203365.
4. Salles MJ, Herv? D, Rivet JM, Longueville S, Millan MJ, Girault JA, Mannoury la Cour C. Transient and rapid activation of Akt/GSK-3? and mTORC1 signaling by D3 dopamine receptor stimulation in dorsal striatum and nucleus accumbens. J Neurochem. 2013 May;125(4):532-44. doi: 10.1111/jnc.12206. Epub 2013 Mar 11. PubMed PMID: 23410496.