Lychnopholide
| Code | Size | Price |
|---|
| TAR-T33021-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lychnopholide is isolated from Vanillosmopsis erythropappa.
CAS:
77448-64-7
Formula:
C20H22O6
Molecular Weight:
358.39
Purity:
0.98
SMILES:
[H][C@]12OC(=O)C(=C)[C@]1([H])[C@H](C[C@@]1(C)OC(=CC1=O)C(C)=C/2)OC(=O)C(C)=CC
References
1. Tupinamb? Branquinho R, Pound-Lana G, Marques Milagre M, Sa?de-Guimar?es DA, Vilela JMC, Spangler Andrade M, de Lana M, Mosqueira VCF. Increased Body Exposure to New Anti-Trypanosomal Through Nanoencapsulation. Sci Rep. 2017 Aug 16;7(1):8429. doi: 10.1038/s41598-017-08469-x. PubMed PMID: 28814794; PubMed Central PMCID: PMC5559493.
2. Branquinho RT, Roy J, Farah C, Garcia GM, Aimond F, Le Guennec JY, Saude-Guimar?es DA, Grabe-Guimaraes A, Mosqueira VC, de Lana M, Richard S. Biodegradable Polymeric Nanocapsules Prevent Cardiotoxicity of Anti-Trypanosomal Lychnopholide. Sci Rep. 2017 Mar 28;7:44998. doi: 10.1038/srep44998. PubMed PMID: 28349937; PubMed Central PMCID: PMC5368638.
3. de Mello CG, Branquinho RT, Oliveira MT, Milagre MM, Sa?de-Guimar?es DA, Mosqueira VC, Lana Md. Efficacy of Lychnopholide Polymeric Nanocapsules after Oral and Intravenous Administration in Murine Experimental Chagas Disease. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5215-22. doi: 10.1128/AAC.00178-16. Print 2016 Sep. PubMed PMID: 27324760; PubMed Central PMCID: PMC4997880.
4. Lachi-Silva L, Sousa JPB, Montanha MC, Sy SKB, Lopes JLC, Silva DB, Lopes NP, Diniz A, Kimura E. Rapid and efficient method for the quantification of lychnopholide in rat plasma by liquid chromatography-tandem mass spectrometry for pharmacokinetic application. Biomed Chromatogr. 2016 Jul;30(7):1092-1096. doi: 10.1002/bmc.3654. Epub 2016 Jan 3. PubMed PMID: 26577838.