Lyngbyatoxin A
| Code | Size | Price |
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| TAR-T33033-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lyngbyatoxin A is an indole alkaloid from blue-green alga Lyngbya majuscula Gomont; responsible for dermatitis known as "swimmers' itch" in Hawaii.
CAS:
70497-14-2
Formula:
C27H39N3O2
Molecular Weight:
437.628
Purity:
0.98
SMILES:
CC(C)C1N(C)c2ccc(c3[nH]cc(CC(CO)NC1=O)c23)C(C)(CCC=C(C)C)C=C
References
1. Wells KN, Videau P, Nelson D, Eiting JE, Philmus B. The influence of sigma factors and ribosomal recognition elements on heterologous expression of cyanobacterial gene clusters in Escherichia coli. FEMS Microbiol Lett. 2018 Aug 1;365(15). doi: 10.1093/femsle/fny164. PubMed PMID: 29982530; PubMed Central PMCID: PMC6279124.
2. Zhang L, Hoshino S, Awakawa T, Wakimoto T, Abe I. Structural Diversification of Lyngbyatoxin A by Host-Dependent Heterologous Expression of the tleABC Biosynthetic Gene Cluster. Chembiochem. 2016 Aug 3;17(15):1407-11. doi: 10.1002/cbic.201600229. Epub 2016 Jun 17. PubMed PMID: 27194569.
3. Videau P, Wells KN, Singh AJ, Gerwick WH, Philmus B. Assessment of Anabaena sp. Strain PCC 7120 as a Heterologous Expression Host for Cyanobacterial Natural Products: Production of Lyngbyatoxin A. ACS Synth Biol. 2016 Sep 16;5(9):978-88. doi: 10.1021/acssynbio.6b00038. Epub 2016 Jun 1. PubMed PMID: 27176641.
4. Zhao Z, deMayo JA, West AM, Balunas MJ, Zweifach A. Development of an Enhanced Phenotypic Screen of Cytotoxic T-Lymphocyte Lytic Granule Exocytosis Suitable for Use with Synthetic Compound and Natural Product Collections. J Biomol Screen. 2016 Jul;21(6):556-66. doi: 10.1177/1087057116643260. Epub 2016 Apr 5. PubMed PMID: 27048485.