Meproscillarin
| Code | Size | Price |
|---|
| TAR-T33291-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Meproscillarin is a glycoside with high bioavailability (about 70%) and an elimination independent of renal function.
CAS:
33396-37-1
Formula:
C31H44O8
Molecular Weight:
544.685
Purity:
0.98
SMILES:
CO[C@H]1[C@H](C)O[C@@H](O[C@H]2CC[C@]3(C)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CCC3=C2)c2ccc(=O)oc2)[C@H](O)[C@@H]1O
References
Alken RG, Belz GG. A comparative dose-effect study with cardiac glycosides assessing cardiac and extracardiac responses in normal subjects. J Cardiovasc Pharmacol. 1984 Jul-Aug;6(4):634-40. PubMed PMID: 6206318.
Belz GG, Aust PE. [Threshold of action of meproscillarin following intravenous administration]. Med Klin. 1980 Jul 18;75(15):551-3. German. PubMed PMID: 7001203.
Rietbrock N. [Metabolism of meproscillarin in man (author's transl)]. Arzneimittelforschung. 1978;28(3a):540-5. German. PubMed PMID: 580585.
Burkert K, Beckmann H. [Plasma concentration and elimination behavior of the cardiac glycoside meproscillarin in patients with liver cirrhosis]. Z Gastroenterol. 1983 Jan;21(1):34-40. German. PubMed PMID: 6845784.