Mersalyl
| Code | Size | Price |
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| TAR-T33297-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Mersalyl is an organic mercurial diuretic.
CAS:
492-18-2
Formula:
C13H16HgNNaO6
Molecular Weight:
505.854
Purity:
0.98
SMILES:
[Na+].COC(CNC(=O)c1ccccc1OCC(O)=O)C[Hg][O-]
References
Joseph SK, Ryan SV, Pierson S, Renard-Rooney D, Thomas AP. The effect of mersalyl on inositol trisphosphate receptor binding and ion channel function. J Biol Chem. 1995 Feb 24;270(8):3588-93. PubMed PMID: 7533153.
Garc?a N, Mart?nez-Abundis E, Pav?n N, Ch?vez E. On the opening of an insensitive cyclosporin A non-specific pore by phenylarsine plus mersalyl. Cell Biochem Biophys. 2007;49(2):84-90. PubMed PMID: 17906363.
Kolbe HV, Kadenbach B. Reaction of mersalyl with mitochondrial proteins under native and denaturing conditions as exemplified by the identification and isolation of the phosphate carrier. Hoppe Seylers Z Physiol Chem. 1981 Dec;362(12):1583-90. PubMed PMID: 7319473.
Agani F, Semenza GL. Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity. Mol Pharmacol. 1998 Nov;54(5):749-54. PubMed PMID: 9804609.