MK 410
| Code | Size | Price |
|---|
| TAR-T33417-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33417-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33417-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
MK 410 is an indomethacin analogue and anti-inflammatory agent that induces changes in the immune system by inhibiting plasma neutral protease activity.
CAS:
40738-05-4
Formula:
C21H23NO3S
Molecular Weight:
369.48
Purity:
0.98
SMILES:
COc1ccc2n(Cc3ccc(SC)cc3)c(C)c(C(C)C(O)=O)c2c1
References
Lassmann G, Curtis J, Liermann B, Mason RP, Eling TE. ESR studies on reactivity of protein-derived tyrosyl radicals formed by prostaglandin H synthase and ribonucleotide reductase. Arch Biochem Biophys. 1993 Jan;300(1):132-6. PubMed PMID: 8380961.
Markey CM, Alward A, Weller PE, Marnett LJ. Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to cyclooxygenase activities. J Biol Chem. 1987 May 5;262(13):6266-79. PubMed PMID: 3106353.
Hart DA, Mannerfeldt J, Babins E. Treatment of mice with indomethacin leads to the appearance of a 125,000 dalton plasma protein with the characteristics of an acute phase reactant. J Clin Lab Immunol. 1987 Jun;23(2):83-90. PubMed PMID: 2442392.
Van Dyke K, Peden D, Van Dyke C, Jones G, Castranova V, Ma J. Inhibition by nonsteroidal antiinflammatory drugs of luminol-dependent human-granulocyte chemiluminescence and [3H]FMLP binding. Effect of sulindac sulfide, indomethacin metabolite, and optical enantiomers (+) and (-) MK830. Inflammation. 1982 Mar;6(1):113-25. PubMed PMID: 7085041.