ML 10
| Code | Size | Price |
|---|
| TAR-T33448-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
ML 10 is is a [18F] positron emission tomography (PET) radiotracer that accumulates in cells presenting apoptosis-specific membrane alterations. [18F]ML-10 allows for the detection of apoptotic cells located in atherosclerotic plaques.
CAS:
1216897-16-3
Formula:
C9H15FO4
Molecular Weight:
206.213
Purity:
0.98
SMILES:
CC(CCCCCF)(C(O)=O)C(O)=O
References
Bao X, Yang Z, Wang S, Zheng Y, Wang M, Gu B, Zhang J, Zhang Y, Zhang Y. The preclinical study of predicting radiosensitivity in human nasopharyngeal carcinoma xenografts by 18F-ML-10 animal- PET/CT imaging. Oncotarget. 2016 Mar 3. doi: 10.18632/oncotarget.7868. [Epub ahead of print] PubMed PMID: 26942701.
Oborski MJ, Laymon CM, Lieberman FS, Drappatz J, Hamilton RL, Mountz JM. First use of (18)F-labeled ML-10 PET to assess apoptosis change in a newly diagnosed glioblastoma multiforme patient before and early after therapy. Brain Behav. 2014 Mar;4(2):312-5. doi: 10.1002/brb3.217. Epub 2014 Feb 12. PubMed PMID: 24683522; PubMed Central PMCID: PMC3967545.
Hyafil F, Tran-Dinh A, Burg S, Leygnac S, Louedec L, Milliner M, Ben Azzouna R, Reshef A, Ben Ami M, Meilhac O, Le Guludec D. Detection of Apoptotic Cells in a Rabbit Model with Atherosclerosis-Like Lesions Using the Positron Emission Tomography Radiotracer [18F]ML-10. Mol Imaging. 2015;14:433-42. PubMed PMID: 26431738.
M?doc M, Dhilly M, Matesic L, Toutain J, Krause-Heuer AM, Delamare J, Fraser BH, Touzani O, Barr? L, Greguric I, Sobrio F. In Vivo Evaluation of Radiofluorinated Caspase-3/7 Inhibitors as Radiotracers for Apoptosis Imaging and Comparison with [18F]ML-10 in a Stroke Model in the Rat. Mol Imaging Biol. 2016 Feb;18(1):117-26. doi: 10.1007/s11307-015-0865-1. PubMed PMID: 26013478.