Mycobactin S
| Code | Size | Price |
|---|
| TAR-T33538-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Mycobactin S is made from metabolic products of the acid-resistant form of Mycobacterium phlei, a tuberculosis bacillus derived originally from the cold-blooded sea turtle. Importantly, it is not based on cell wall fragments or killed bacteria.
CAS:
26769-11-9
Formula:
C44H69N5O10
Molecular Weight:
828.061
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCC=C/C(=O)N(O)CCCC[C@H](NC(=O)[C@@H]1COC(=N1)c1ccccc1O)C(=O)O[C@@H](C)CC(=O)N[C@H]1CCCCN(O)C1=O
References
White AJ, Snow GA. Isolation of mycobactinss from various mycobacteria. The properties of mycobactin S and H. Biochem J. 1969 Mar;111(5):785-92. PubMed PMID: 5783478; PubMed Central PMCID: PMC1187608.
Walz AJ, M?llmann U, Miller MJ. Synthesis and studies of catechol-containing mycobactin S and T analogs. Org Biomol Chem. 2007 May 21;5(10):1621-8. Epub 2007 Apr 19. PubMed PMID: 17571193.
Madigan CA, Martinot AJ, Wei JR, Madduri A, Cheng TY, Young DC, Layre E, Murry JP, Rubin EJ, Moody DB. Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis. PLoS Pathog. 2015 Mar 27;11(3):e1004792. doi: 10.1371/journal.ppat.1004792. eCollection 2015 Mar. PubMed PMID: 25815898; PubMed Central PMCID: PMC4376628.
Madigan CA, Cheng TY, Layre E, Young DC, McConnell MJ, Debono CA, Murry JP, Wei JR, Barry CE 3rd, Rodriguez GM, Matsunaga I, Rubin EJ, Moody DB. Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1257-62. doi: 10.1073/pnas.1109958109. Epub 2012 Jan 9. PubMed PMID: 22232695; PubMed Central PMCID: PMC3268331.