N-Benzyloxycarbonylglycine
Code | Size | Price |
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TAR-T33604-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
N-benzyloxycarbonylglycine is a drug-lipid conjugates designed to promote brain penetration based on its lipophilicity and resemblance to lipids in biological membranes[1].
CAS:
1138-80-3
Formula:
C10H11NO4
Molecular Weight:
209.201
Purity:
0.9988
SMILES:
OC(=O)CNC(=O)OCc1ccccc1
References
Sussan S, Dagan A, Bialer M. Pharmacokinetic analysis and anticonvulsant activity of glycine and glycinamide derivatives. Epilepsy Res. 1999 Jan;33(1):11-21. PubMed PMID: 10022362.
Scriba GK, Lambert DM. Synthesis and anticonvulsant activity of N-benzyloxycarbonyl-amino acid prodrugs of phenytoin. J Pharm Pharmacol. 1999 May;51(5):549-53. PubMed PMID: 10411214.
Lambert DM. Rationale and applications of lipids as prodrug carriers. Eur J Pharm Sci. 2000 Oct;11 Suppl 2:S15-27. Review. PubMed PMID: 11033424.
Lambert DM. Rationale and applications of lipids as prodrug carriers. Eur J Pharm Sci. 2000 Oct;11 Suppl 2:S15-27.