NeuroSensor 521
| Code | Size | Price |
|---|
| TAR-T33655-5mg | 5mg | £312.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33655-25mg | 25mg | £701.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
NeuroSensor 521 is a fluorescent turn-on sensor. It acts by binding catecholamines such as dopamine and norepinephrine more tightly than other biogenic amines such as glutamate.
CAS:
1428730-05-5
Formula:
C21H21NO4
Molecular Weight:
351.402
Purity:
0.98
SMILES:
CCN(CC)c1ccc2c(-c3ccc(OC)cc3)c(C=O)c(=O)oc2c1
References
Hettie KS, Glass TE. Coumarin-3-aldehyde as a scaffold for the design of tunable PET-modulated fluorescent sensors for neurotransmitters. Chemistry. 2014 Dec 22;20(52):17488-99. doi: 10.1002/chem.201403128. Epub 2014 Oct 24. PubMed PMID: 25346467.
Hettie KS, Liu X, Gillis KD, Glass TE. Selective catecholamine recognition with NeuroSensor 521: a fluorescent sensor for the visualization of norepinephrine in fixed and live cells. ACS Chem Neurosci. 2013 Jun 19;4(6):918-23. doi: 10.1021/cn300227m. Epub 2013 Mar 25. PubMed PMID: 23527575; PubMed Central PMCID: PMC3708293.