Niludipine
| Code | Size | Price |
|---|
| TAR-T33673-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33673-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33673-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Nirudipine is a double (2-propoxyethyl) analogist of nifedipine and a calcium channel blocker, which is also a safe anti-angina Ca2+ antagonist with a broad range of efficacy for all types of angina. At the same time, Niludipine is a highly effective drug for the treatment of ischemic heart disease and essential hypertension.
CAS:
22609-73-0
Formula:
C25H34N2O8
Molecular Weight:
490.553
Purity:
0.98
SMILES:
CCCOCCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCOCCC
References
Ohneda A, Kobayashi T, Nihei J. Effects of Ca antagonists, nifedipine, niludipine and verapamil, on endocrine function of the pancreas. Tohoku J Exp Med. 1983 Jun;140(2):153-9. PubMed PMID: 6351351.
Ichihara K, Sakai K, Abiko Y. Effect of nifedipine and niludipine on myocardial pH in the ischemic canine heart. Arch Int Pharmacodyn Ther. 1986 Mar;280(1):58-73. PubMed PMID: 3718082.
Yasuda H, Tomita T, Fujita K, Shibata J, Tateda K, Yokota H, Igarashi T, Ogasawara S, Yamazaki M, Oyama Y. Clinical efficacy of niludipine in the treatment of angina pectoris. Arzneimittelforschung. 1984;34(5):614-9. PubMed PMID: 6540580.
Kusano E, Asano Y, Takeda K, Terao N, Hosoda S. Acute and chronic hypotensive effects of nifedipine and niludipine in hypertensive patients with chronic renal failure. Arzneimittelforschung. 1984;34(5):624-9. PubMed PMID: 6432001.