TargetMol

Okilactomycin

Product Code:
 
TAR-T33786
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T33786-5mg5mg£850.00
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Further Information

Bioactivity:
Okilactomycin is a biochemical.
CAS:
111367-04-5
Formula:
C24H32O6
Molecular Weight:
416.514
Purity:
0.98
SMILES:
[H][C@]12O[C@]3([H])[C@H](C)C[C@H](C)CCC[C@@]4([H])C=C([C@@H](C)C[C@@]14OC(=O)[C@@]2(C)C(=O)C3=C)C(O)=O

References

Zhang C, Ondeyka JG, Zink DL, Basilio A, Vicente F, Salazar O, Genilloud O, Dorso K, Motyl M, Byrne K, Singh SB. Discovery of okilactomycin and congeners from Streptomyces scabrisporus by antisense differential sensitivity assay targeting ribosomal protein S4. J Antibiot (Tokyo). 2009 Feb;62(2):55-61. doi: 10.1038/ja.2008.8. Epub 2009 Jan 9. PubMed PMID: 19132063. Niu D, Hoye TR. A concise total synthesis of (?)- and (-)-okilactomycin D. Org Lett. 2012 Feb 3;14(3):828-31. doi: 10.1021/ol203355g. Epub 2012 Jan 24. PubMed PMID: 22273402; PubMed Central PMCID: PMC3272355. Smith AB 3rd, Bosanac T, Basu K. Evolution of the total synthesis of (-)-okilactomycin exploiting a tandem oxy-cope rearrangement/oxidation, a Petasis-Ferrier union/rearrangement, and ring-closing metathesis. J Am Chem Soc. 2009 Feb 18;131(6):2348-58. doi: 10.1021/ja8084669. PubMed PMID: 19170499; PubMed Central PMCID: PMC2697663. Tenenbaum JM, Morris WJ, Custar DW, Scheidt KA. Synthesis of (-)-okilactomycin by a Prins-type fragment-assembly strategy. Angew Chem Int Ed Engl. 2011 Jun 20;50(26):5892-5. doi: 10.1002/anie.201102037. Epub 2011 May 10. PubMed PMID: 21560215; PubMed Central PMCID: PMC3219920.