TargetMol

[6]-Gingerol

Product Code:
 
TAR-T3405
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T3405-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T3405-20mg20mg£167.00
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Further Information

Bioactivity:
6-Gingerol, an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for Yous tumors in the pancreas, ovaries, breast tissue, the bowel, among other tissues.
CAS:
23513-14-6
Formula:
C17H26O4
Molecular Weight:
294.4
Pathway:
Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Apoptosis
Purity:
0.9931
SMILES:
CCCCC[C@@H](CC(=O)CCc1cc(c(cc1)O)OC)O
Target:
Apoptosis; AMPK

References

Kamaruddin M S H, Chong G H, Umanan F, et al.Enhancement of 6-gingerol extraction from Bentong ginger using supercritical carbon dioxide.Journal of CO2 Utilization.2023, 72: 102505. Chang KW, et al. 6-Gingerol modulates proinflammatory responses in dextran sodium sulfate (DSS)-treated Caco-2 cells and experimental colitis in mice through adenosine monophosphate-activated protein kinase (AMPK) activation. Food Funct. 2015 Oct;6(10):3334-41. Radhakrishnan EK, et al. [6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling. PLoS One. 2014 Aug 26;9(8):e104401. Fan J, et al. 6-Gingerol inhibits osteosarcoma cell proliferation through apoptosis and AMPK activation. Tumour Biol. 2015 Feb;36(2):1135-41. Zhang B, Zhao J, Wang Z, et al. Identification of Multi-Target Anti-AD Chemical Constituents From Traditional Chinese Medicine Formulae by Integrating Virtual Screening and In Vitro Validation. Frontiers in Pharmacology. 2021?1781