Pipotiazine
| Code | Size | Price |
|---|
| TAR-T34072-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34072-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34072-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Pipotiazine has less sedating and a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics among the different phenothiazine derivatives. However, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients.
CAS:
39860-99-6
Formula:
C24H33N3O3S2
Molecular Weight:
475.67
Purity:
0.98
SMILES:
CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCC(CCO)CC3)c2c1
References
Haddad P, Taylor M, Patel MX, Taylor D. Guidance on switching away from Piportil Depot? (pipotiazine palmitate) injection. Br J Psychiatry. 2015 Jun;206(6):521. doi: 10.1192/bjp.206.6.521. PubMed PMID: 26034183.
De Schepper PJ, Vranckx C, Verbeeck R, Van den Berghe ML. Pipotiazine pharmacokinetics after p.o. and i.v. administration in man. Correlation between blood levels and effect on the handwriting area. Arzneimittelforschung. 1979;29(7):1056-62. PubMed PMID: 40577.
Dinesh M, David A, Quraishi SN. Depot pipotiazine palmitate and undecylenate for schizophrenia. Cochrane Database Syst Rev. 2004 Oct 18;(4):CD001720. Review. PubMed PMID: 15495016.
Tavitian E, Peyrin L, Dalmaz Y, Favre R, De Haut M, Cottet-Emard JM. Free and conjugated 3,4-dihydroxyphenylacetic acid and homovanillic acid in brain dopaminergic areas at basal state and after pipotiazine activation. J Neural Transm. 1986;65(3-4):261-75. PubMed PMID: 2872271.