Pleurosine
| Code | Size | Price |
|---|
| TAR-T34088-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Pleurosine is a catharanthuseus alkaloid.
CAS:
39608-80-5
Formula:
C46H56N4O10
Molecular Weight:
824.972
Purity:
0.98
SMILES:
CC[C@]12CN3(=O)C[C@@H](C[C@@](OC(C)=O)(c4[nH]c5ccccc5c4CC3)c3cc4c(cc3OC)N(C)C3C44CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)[C@H]1O2
References
El-Sayed A, Handy GA, Cordell GA. Catharanthus alkaloids, XXXVIII. Confirming structural evidence and antineoplastic activity of the bisindole alkaloids leurosine-N'b-oxide (pleurosine), roseadine and vindolicine from Catharanthus roseus. J Nat Prod. 1983 Jul-Aug;46(4):517-27. PubMed PMID: 6631435.
Kulanthaivel P, Barbuch RJ, Davidson RS, Yi P, Rener GA, Mattiuz EL, Hadden CE, Goodwin LA, Ehlhardt WJ. Selective reduction of N-oxides to amines: application to drug metabolism. Drug Metab Dispos. 2004 Sep;32(9):966-72. PubMed PMID: 15319338.