Primapterin
| Code | Size | Price |
|---|
| TAR-T34132-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Primapterin, 7-Substituted pterins, is a new type of mammalian pteridines.
CAS:
2582-88-9
Formula:
C9H11N5O3
Molecular Weight:
237.219
Purity:
0.98
SMILES:
CC(O)C(O)c1cnc2c(n1)[nH]c(N)nc2=O
References
Allegri G, Costa Netto HJ, Ferreira Gomes LN, Costa de Oliveira ML, Scalco FB, de Aquino Neto FR. Determination of six pterins in urine by LC-MS/MS. Bioanalysis. 2012 Jul;4(14):1739-46. doi: 10.4155/BIO.12.131. PubMed PMID: 22877220.
Pey AL, Martinez A, Charubala R, Maitland DJ, Teigen K, Calvo A, Pfleiderer W, Wood JM, Schallreuter KU. Specific interaction of the diastereomers 7(R)- and 7(S)-tetrahydrobiopterin with phenylalanine hydroxylase: implications for understanding primapterinuria and vitiligo. FASEB J. 2006 Oct;20(12):2130-2. Epub 2006 Aug 25. PubMed PMID: 16935936.
Ayling JE, Bailey SW, Boerth SR, Giugliani R, Braegger CP, Th?ny B, Blau N. Hyperphenylalaninemia and 7-pterin excretion associated with mutations in 4a-hydroxy-tetrahydrobiopterin dehydratase/DCoH: analysis of enzyme activity in intestinal biopsies. Mol Genet Metab. 2000 Jul;70(3):179-88. PubMed PMID: 10924272.
Opladen T, Hoffmann GF, Blau N. An international survey of patients with tetrahydrobiopterin deficiencies presenting with hyperphenylalaninaemia. J Inherit Metab Dis. 2012 Nov;35(6):963-73. doi: 10.1007/s10545-012-9506-x. Epub 2012 Jun 23. PubMed PMID: 22729819.