RSR4
| Code | Size | Price |
|---|
| TAR-T34421-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34421-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34421-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
RSR4 is one of the most effective allosteric effectors of hemoglobin.
CAS:
131179-94-7
Formula:
C18H17Cl2NO4
Molecular Weight:
382.24
Purity:
0.98
SMILES:
CC(C)(Oc1ccc(CC(=O)Nc2cc(Cl)cc(Cl)c2)cc1)C(O)=O
References
Kiger L, Dumoulin A, Edelstein SJ, Abraham DJ, Prom? D, Poyart C, Marden MC, Pagnier J. Chimeric beta-EF3-alpha hemoglobin (Psi): energetics of subunit interaction and ligand binding. Biochemistry. 1998 May 19;37(20):7328-39. PubMed PMID: 9585547.
Safo MK, Boyiri T, Burnett JC, Danso-Danquah R, Moure CM, Joshi GS, Abraham DJ. X-ray crystallographic analyses of symmetrical allosteric effectors of hemoglobin: compounds designed to link primary and secondary binding sites. Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):634-44. Epub 2002 Mar 22. PubMed PMID: 11914488.
Khandelwal SR, Randad RS, Lin PS, Meng H, Pittman RN, Kontos HA, Choi SC, Abraham DJ, Schmidt-Ullrich R. Enhanced oxygenation in vivo by allosteric inhibitors of hemoglobin saturation. Am J Physiol. 1993 Oct;265(4 Pt 2):H1450-3. PubMed PMID: 8238433.
Wagner S, Bernhardt A, Leuendorf JE, Drewke C, Lytovchenko A, Mujahed N, Gurgui C, Frommer WB, Leistner E, Fernie AR, Hellmann H. Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis. Plant Cell. 2006 Jul;18(7):1722-35. Epub 2006 Jun 9. PubMed PMID: 16766694; PubMed Central PMCID: PMC1488916.