Rumbrin
| Code | Size | Price |
|---|
| TAR-T34450-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rumbrin is a cytoprotective compound produced by Auxarthron umbrinum.
CAS:
148528-19-2
Formula:
C20H20ClNO3
Molecular Weight:
357.83
Purity:
0.98
SMILES:
COc1cc(oc(=O)c1C)C(C)=C/C=C/C=C/C=C/c1[nH]ccc1Cl
References
Yamagishi Y, Shindo K, Kawai H. Rumbrin, a new cytoprotective substance produced by Auxarthron umbrinum. II. Physico-chemical properties and structure determination. J Antibiot (Tokyo). 1993 Jun;46(6):888-91. PubMed PMID: 8344869.
Clark BR, O'Connor S, Fox D, Leroy J, Murphy CD. Production of anticancer polyenes through precursor-directed biosynthesis. Org Biomol Chem. 2011 Sep 21;9(18):6306-11. doi: 10.1039/c1ob05667k. Epub 2011 Jul 26. PubMed PMID: 21792395.
Yamagishi Y, Matsuoka M, Odagawa A, Kato S, Shindo K, Mochizuki J. Rumbrin, a new cytoprotective substance produced by Auxarthron umbrinum. I. Taxonomy, production, isolation and biological activities. J Antibiot (Tokyo). 1993 Jun;46(6):884-7. PubMed PMID: 8344868.
Clark BR, Murphy CD. Biosynthesis of pyrrolylpolyenes in Auxarthron umbrinum. Org Biomol Chem. 2009 Jan 7;7(1):111-6. doi: 10.1039/b813236d. Epub 2008 Oct 31. PubMed PMID: 19081953.