S 2484
| Code | Size | Price |
|---|
| TAR-T34465-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
S 2484 is a chromogranic specific granulocyte elastase substrate.
CAS:
86190-22-9
Formula:
C21H29N5O7
Molecular Weight:
463.491
Purity:
0.98
SMILES:
CC(C)[C@H](N(C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCC(O)=O)c1ccc(cc1)[N+]([O-])=O)C(N)=O
References
Hamanaka K, Toki N, Takasugi S, Sumi H. Effect of plant SH-protease on human polymorphonuclear leukocyte granule elastase. J Dermatol. 1984 Dec;11(6):523-8. PubMed PMID: 6399052.
Regan J, McGarry D, Bruno J, Green D, Newman J, Hsu CY, Kline J, Barton J, Travis J, Choi YM, Volz F, Pauls H, Harrison R, Zilberstein A, Ben-Sasson SA, Chang M. Anionic- and lipophilic-mediated surface binding inhibitors of human leukocyte elastase. J Med Chem. 1997 Oct 10;40(21):3408-22. PubMed PMID: 9341916.
Tanaka H, Shimazu T, Sugimoto H, Yoshioka T, Sugimoto T. A sensitive and specific assay for granulocyte elastase in inflammatory tissue fluid using L-pyroglutamyl-L-prolyl-L-valine-p-nitroanilide. Clin Chim Acta. 1990 Feb 28;187(2):173-80. PubMed PMID: 2317934.
Figueredo CM, Gustafsson A, Asman B, Bergstr?m K. Increased release of elastase from in vitro activated peripheral neutrophils in patients with adult periodontitis. J Clin Periodontol. 1999 Apr;26(4):206-11. PubMed PMID: 10223390.