Safotibant

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TargetMol
Product Code: TAR-T34485
Supplier: TargetMol
CodeSizePrice
TAR-T34485-1mg1mg£188.00
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TAR-T34485-5mg5mg£352.00
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Quantity:
TAR-T34485-10mg10mg£496.00
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Quantity:
TAR-T34485-25mg25mg£760.00
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Quantity:
TAR-T34485-50mg50mg£1,018.00
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Quantity:
TAR-T34485-100mg100mg£1,348.00
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Quantity:
TAR-T34485-500mg500mg£2,633.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Safotibant?LF-22-0542?is a bradykinin B1 receptor antagonist being developed for the topical treatment of diabetic macular edema.
CAS:
633698-99-4
Formula:
C25H34N4O5S
Molecular Weight:
502.63
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
COc1cc(C)c(c(C)c1)S(=O)(=O)N(C)CCOCC(=O)N(C)Cc1ccc(cc1)C1=NCCN1
Target:
Bradykinin Receptor

References

Pouliot M, et al. Ocular application of the kinin B1 receptor antagonist LF22-0542 inhibits retinal inflammation and oxidative stress in streptozotocin-diabetic rats. PLoS One. 2012;7(3):e33864. Mahmudpour M, et al. COVID-19 cytokine storm: The anger of inflammation. Cytokine. 2020;133:155151.